? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? AiiA LsrB LasR YtbI PvdQ PvdQ PqsC SdiA SwrR PctA QuiP AhyR AiiM VsmR YtbR CepI LsrB PqsE QuiP SdiA PagR VsmI AiiM PqsA PqsE VanM CepI YpsI PagI VsmI QuiP BviI CepR QuiP AhyI TlpQ CepR EasI AiiA LasR LuxR OpaR CepI AiiA YpsR PqsR AhyR SdiA BviI YtbI PagI BviI PqsA CroI PqsD ? AhyI YenI LuxR AiiA SwrR HacB AiiA AhyR AhyI SwrR CepR YtbR AhyI PagI CepR VanI AhlK YenR LuxR CepR SwrI BviR VanM SdiA PqsC CepR CepI PqsR PqsB LasR AiiA PvdQ SdiA SwrR CepI VanR CepR BviR CroI Tryptophanase TnaA SwrR CroI PqsR CepR LasI PctA PagI PvdQ SwrR AhyI AhyR SdiA PagR VsmR SpnR QuiP AhlK SpnI TlpQ AiiM BviR CepR Tryptophanase TnaA PqsD YtbR SpnI CepR SwrR LuxS CepR AhyR SpnI LuxR CepR PvdQ CepI CepI LsrB PqsB AhyI LasI CepR SdiA YenI SwrI LasR AhyR YpsI SpnI YpsR EasI PagR YtbI HacB EasR EasR PagR VanP CroI YenR CepR AhyI AhyR SdiA AiiM PagR VsmR SpnR QuiP LuxR CepI C10-HSL PQS C7-AQ 3-OH-C6-HSL C7-HSL C14-HSL 3-oxo-C4-HSL 3-oxo-C14-HSL C8-HSL C6-HSL C16-HSL 3-oxo-C12-HSL C12-HSL 3-oxo-C6-HSL 3-oxo-C8-HSL C4-HSL AI-2 C18-HSL 3-OH-C4-HSL indole 3-oxo-C10-HSL increased proteolytic activity attenuated virulence inhibition of exoprotease production reduction in gall size of gypsophila altered major characteristics of respiration and energetics, and decreased mitochondrial membrane potential in fibroblasts and intestinal epithelial cells increased motility upregulation of virulence factors increased biofilm formation inhibited biofilm formation induced fragmentation of mitochondria , disruption of cristae and inner membrane ultrastructure in fibroblasts and intestinal epithelial cells decreased biofilm formation increased siderophore production increased antibiotic production regulated biofilm formation induced swarming motility increased swarming motility increased chitinase production increased biofilm formation increased proteolytic activity decreased virulence increased biofilm formation attenuated production of Pseudomonas quinolone signal upregulation of prodigiosin, nuclease, biosurfactant, sliding motility decreased expression of metalloprotease empA regulation of motility increased the transition rate to VBNC state inhibited Staphylococcus epidermidis biofilm, initial attachment, and EPS production increased acid tolerance repressed swarming motility upregulation of virulence determinant genes increased cell invasion increased proteolytic activity induced apoptosis of macrophages and neutrophiles enhanced biofilm formation repressed membrane vesicle production increased maceration of Allium cepa onion due to decrease in production of extracellular polygalacturonase modulated antibiotic tolerance increased biofilm formation increased EPS production decreased transcription of T3SS effectors increased biofilm thickness